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Eyes

MPS I Hurler, Hurler-Scheie and Scheie

People with MPS I experience clouding of the cornea which is caused by stored mucopolysaccharides and can lead to significant visual disability. Some people cannot tolerate bright lights as the clouding causes bending of the light which affects the vision, tinted glasses may be helpful in such circumstances.

Severe corneal clouding may reduce sight, especially in dim light, a loss of night vision is common, cornea transplants can be a treatment option. Glaucoma, which is abnormally high pressure in the eye, may occur and cause damage to the retina, it is advisable to have regular assessment for possible glaucoma.Often children with Hurler disease do not want to sleep in the dark or are afraid when waking up at night, using a night light may prove beneficial.

MPS II Hunter

People with MPS II experience clouding of the cornea which is caused by stored mucopolysaccharides and can lead to significant visual disability. Some people cannot tolerate bright lights as the clouding causes bending of the light which affects the vision, tinted glasses may be helpful in such circumstances.

Severe corneal clouding may reduce sight, especially in dim light, a loss of night vision is common, cornea transplants can be a treatment option. Glaucoma, which is abnormally high pressure in the eye, may occur and cause damage to the retina, it is advisable to have regular assessment for possible glaucoma.Often children with Hurler disease do not want to sleep in the dark or are afraid when waking up at night, using a night light may prove beneficial.

MPS III Sanfilippo

Corneal clouding does not occur in the eyes as it does in other MPS diseases. Often children with MPS III do not want to sleep in the dark or are afraid when waking up at night, using a night light may prove beneficial.

Advice for professionals

We want to give you the tools to be able to learn about MPS, Fabry and related diseases in order for children with the condition to receive a faster diagnosis.

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MPS IV Morquio

People with MPS IV can experience clouding of the cornea which is caused by stored mucopolysaccharides and can lead to significant visual disability. Some people cannot tolerate bright lights as the clouding causes bending of the light which affects the vision, tinted glasses may be helpful in such circumstances.

Severe corneal clouding may reduce sight, especially in dim light, a loss of night vision is common, cornea transplants can be a treatment option. Often children with MPS IV do not want to sleep in the dark or are afraid when waking up at night, using a night light may prove beneficial.

MPS VI Maroteaux-Lamy

People with MPS VI experience clouding of the cornea which is caused by stored mucopolysaccharides and can lead to significant visual disability. Some people cannot tolerate bright lights as the clouding causes bending of the light which affects the vision, tinted glasses may be helpful in such circumstances. Severe corneal clouding may reduce sight, especially in dim light, a loss of night vision is common, cornea transplants can be a treatment option.

Occasionally vision deteriorates due to damage to the retina or the optic nerve. Often children with MPS VI do not want to sleep in the dark or are afraid when waking up at night, using a night light may prove beneficial.

MPS VII Sly

People with MPS VII experience clouding of the cornea which is caused by stored mucopolysaccharides and can lead to significant visual disability. Some people cannot tolerate bright lights as the clouding causes bending of the light which affects the vision, tinted glasses may be helpful in such circumstances.

Some people cannot tolerate bright lights as the clouding causes uneven refraction of light. A loss of night vision is common which may also be due to damage of the retina. Severe corneal clouding may reduce sight, especially in dim light, a loss of night vision is common, cornea transplants can be a treatment option.

Glaucoma, which is abnormally high pressure in the eye, may occur and cause damage to the retina, it is advisable to have regular assessment for possible glaucoma. Often children with MPS VII do not want to sleep in the dark or are afraid when waking up at night, using a night light may prove beneficial

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