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About the conditions

The MPS Society supports individuals affected by 27 rare lysosomal storage diseases. This includes the seven Mucopolysaccharide (MPS) diseases, Fabry and related diseases such as Mucolipidosis (ML), LAL D, GM 1 Gangliosidosis and more.

Lysosomes are the recycling plants of our cells.  When working normally they continuously break down old materials to be recycled. In Lysosomal Storage Disorders (LSDs) this process no longer works the way it should.

When the Lysosomes are not working in the way that they should, old materials build up in the cells and, over time, cause damage. This damage results in the progressive signs and symptoms we see in the conditions that we support.

You can find out more about the individual conditions we support below:

MPS VI Maroteaux Lamy

On this page you can find general information about the condition, latest news, updates and stories and a list of relevant resources and events.
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MPS VII Sly

On this page you can find general information about the condition, latest news, updates and stories and a list of relevant resources and events.
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Mucolipidosis Type I

Mucolipidosis type I (ML I), also known as sialidosis, is a rare inherited lysosomal storage disease, belonging to the group of oligosaccharidosis that...
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Mucolipidosis Type II

Mucolipidosis Type II (ML II) is one of the lysosomal storage diseases known collectively as mucolipidoses and is also referred to as I-Cell Disease. ML...
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Mucolipidosis Type III

Mucolipidosis Type III (ML III) is one of the lysosomal storage diseases known collectively as mucolipidoses and is sometimes referred to as Pseudo-Hurler...
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Mucolipidosis Type IV

Mucolipidosis type IV (ML IV) also known as ganglioside sialidase deficiency and sialolipidosis, is an inherited lysosomal storage disease, belonging to...
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Multiple sulphatase deficiency

Multiple sulphatase deficiency (MSD) is a lysosomal storage diseases closely related to the mucopolysaccharidoses in which all twelve of the known...
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Related conditions

The MPS Society supports 27 MPS and related diseases including the Mucolipidoses, other ‘storage diseases’ and the following conditions which...
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Winchester Syndrome

Winchester syndrome is a rare inherited disease characterised by a loss of bone tissue (osteolysis), particularly in the hands and feet. Although it is...
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