Mucopolysaccharidoses (MPS) and related lysosomal storage disorders remain among the most complex conditions to manage, treat, and monitor. The expert meeting, held on the opening day of the 2025 MPS Conference, was convened in response to ongoing concerns and challenges in key clinical areas, including airway management, cardiac disease, orthopaedic complications, and neurological involvement. In addition to exploring these pressing clinical issues, the meeting will provide a platform for dialogue on emerging topics such as research developments, innovation in care, childhood dementia, and in utero enzyme replacement therapy (ERT).
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